The Importance Of Flash Columns In Chromatography
The rapid chromatographic method is a technology widely used in the separation and purification of active target compounds, such as organic compounds, natural products, and biological macromolecules. Rapid chromatographic method has the advantages of easy-operation, low-price, and fast-analysis. In the application of purifying organic compounds, there is almost no other technology that is better than rapid chromatographic method. The rapid chromatographic method is a typical low-pressure technology. The flash column is filled with silica gel adsorbent with a particle size of 40-60 um. The smaller particle size is suitable for the low-viscosity mobile phase.
Rapid chromatography is often used in TLC. The demand for rapid chromatography mainly comes from the pharmaceutical industry, biotechnology, and academic institutions, which occupy 84% of the market share of rapid chromatography. In the pharmaceutical industry, rapid chromatography is widely used, including the purification of a small number of compounds, polypeptides and natural products.
In the process of chromatographic analysis, a flash liquid chromatographic column with high separation performance and stability plays a key role in establishing a reliable separation and purification process. A rapid chromatographic column with high separation performance can ensure maximum separation of target compounds and impurities.
The uniform distribution of the packing size in the flash columns ensures the normal column pressure when using. Manufacturers will test many times with precise regulations when making the flash column to ensure high recovery and perfect reproducibility of chromatographic columns and separate the target compounds effectively.